Group |
Human: GTEx group |
Tissue |
Anterior Cingulate Cortex mRNA |
Gene Symbol |
CHRNA3 |
Aliases |
Wikidata: BAIPRCK; LNCR2; NACHRA3; PAOD2; (a)3; A730007P14Rik; Acra-3; Acra3 |
|
GeneNetwork: LNCR2; NACHRA3; PAOD2 |
Location |
Chr 15 @ 78.887647 Mb on the minus strand |
Summary |
This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009] |
Database |
GTEx Human Anterior Cingulate Cortex (Apr14) RPKM
|
Resource Links |
Gene
OMIM
GeneMANIA
Protein Atlas
Rat Genome DB
GTEx Portal
BioGPS
STRING
PANTHER
Gemma
ABA
EBI GWAS
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