Group |
Rat: HXBBXH group |
Tissue |
Kidney mRNA |
Gene Symbol |
Chrna3 |
Aliases |
Wikidata: BAIPRCK; LNCR2; NACHRA3; PAOD2; (a)3; A730007P14Rik; Acra-3; Acra3 |
|
GeneNetwork: Not available |
Location |
Chr 8 @ 55.401778 Mb on the minus strand |
Summary |
Enables acetylcholine binding activity; heterocyclic compound binding activity; and postsynaptic neurotransmitter receptor activity. Involved in several processes, including acetylcholine receptor signaling pathway; regulation of synaptic vesicle exocytosis; and response to nicotine. Located in several cellular components, including neuronal cell body; plasma membrane raft; and postsynaptic density. Part of acetylcholine-gated channel complex. Is active in cholinergic synapse and dopaminergic synapse. Is integral component of postsynaptic specialization membrane. Used to study visual epilepsy. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit). [provided by Alliance of Genome Resources, Apr 2022] |
Database |
MDC/CAS/ICL Kidney 230A (Apr05) RMA 2z+8
|
Target Score |
BLAT Specificity
:
20.000
Score: 232.000
|
Resource Links |
Gene
OMIM
GeneMANIA
Protein Atlas
Rat Genome DB
GTEx Portal
PhenoGen
UCSC
BioGPS
STRING
PANTHER
Gemma
EBI GWAS
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