Group |
Mouse: BXD group |
Tissue |
Hypothalamus mRNA |
Gene Symbol |
Chrna3 |
Aliases |
Wikidata: BAIPRCK; LNCR2; NACHRA3; PAOD2; (a)3; A730007P14Rik; Acra-3; Acra3 |
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GeneNetwork: Chrna3; (a)3; A730007P14Rik; Acra-3; Acra3 |
Location |
Chr 9 @ 55.006443 Mb on the minus strand |
Summary |
Enables acetylcholine-gated cation-selective channel activity. Acts upstream of or within several processes, including activation of transmembrane receptor protein tyrosine kinase activity; behavioral response to nicotine; and chemical synaptic transmission. Is integral component of postsynaptic specialization membrane. Part of acetylcholine-gated channel complex. Is active in cholinergic synapse. Is expressed in several structures, including central nervous system; gut; myenteric nerve plexus; paravertebral ganglion; and retina. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit). [provided by Alliance of Genome Resources, Apr 2022] |
Database |
INIA Hypothalamus Affy MoGene 1.0 ST (Nov10) PCA Test v080513
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Resource Links |
Gene
OMIM
GeneMANIA
Protein Atlas
Rat Genome DB
GTEx Portal
UCSC
BioGPS
STRING
PANTHER
Gemma
ABA
EBI GWAS
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